Complete bone regeneration in hemophilic pseudotumor of the mandible. Issue 5 (6th November 2015)

• Record Type: Journal Article
• Authors: Otsuka, Hiroki; Ozeki, Michio; Kanda, Kaori; Hori, Tomohiro; Kawamoto, Norio; Saigo, Chiemi; Kato, Hiroki; Makita, Hiroki; Shibata, Toshiyuki; Fukao, Toshiyuki
• Is Part Of: Pediatrics international. Volume 58:Issue 5(2016)
• Page Start: 406
• Page End: 408
• Publication Date: 2015-11-06
• Subjects: bone regeneration -- diagnostic imaging -- factor VIII -- hemophilia -- mandible; Pediatrics -- Periodicals; 618.92
• DOI: 10.1111/ped.12820
• Languages: English
• ISSNs: 1328-8067

Abstract

Abstract: Hemophilic pseudotumor (HP) is rare, seen in 1–2% of patients with hemophilia, and is extremely uncommon in the mandible. A 6‐year‐old boy with moderate hemophilia A presented to our hospital with left mandibular swelling. Based on clinical and radiological findings, a tentative diagnosis of HP was made. After factor VIII administration, the lesion was curetted and HP was confirmed on histopathology. The patient was treated with twice‐weekly factor VIII until the lesion had completely resolved and bone had regenerated at 1 year. The best treatment for HP is not established; however, appropriate initial treatment and postoperative prophylaxis are effective.