Front Cover: Pd/Zn Co‐catalyzed Asymmetric Ring‐Opening Reactions of Aza/Oxabicyclic Alkenes with Oximes (Asian J. Org. Chem. 1/2019). Issue 1 (9th January 2019)

• Record Type: Journal Article
• Authors: Shen, Guoli; Khan, Ruhima; Yang, Fan; Yang, Yong; Pu, Dongdong; Gao, Yang; Zhan, Yong; Luo, Yang; Fan, Baomin
• Is Part Of: Asian journal of organic chemistry. Volume 8:Issue 1(2019)
• Page Start: 1
• Page End: 1
• Publication Date: 2019-01-09
• Subjects: ring-opening reactions -- norbornadienes -- oximes -- asymmetric synthesis -- asymmetric catalysis; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201800696
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract : An asymmetric ring‐opening reaction of aza/oxabicyclic alkenes with aromatic oximes was established. The reaction was co‐catalyzed by Pd(OAc)2 and zinc triflate with ( R )‐DIFLUORPHOS as the chiral ligand, affording cis ‐stereoselective asymmetric ring‐opening products. A synthetic application of this method has been demonstrated by transforming the products to chiral amino alcohols and chiral vicinal diols. More information can be found in the Communication by Yong Yang, Baomin Fan et al. onpage 97 in Issue 1, 2019 (DOI:10.1002/ajoc.201800569 ).