Heart Transplantation in a Fontan Patient Using a Hepatitis C-Positive Donor. Issue 4 (July 2019)

• Record Type: Journal Article
• Authors: Menachem, Jonathan N.; Bichell, David P.; Frischhertz, Benjamin; Shah, Ashish S.; Schlendorf, Kelly
• Is Part Of: World journal for pediatric & congenital heart surgery. Volume 10:Issue 4(2019)
• Page Start: 504
• Page End: 504
• Publication Date: 2019-07
• Subjects: Pediatric cardiology -- Periodicals; Congenital heart disease in children -- Periodicals; Heart -- Abnormalities -- Surgery -- Periodicals; Heart -- Surgery -- Periodicals; Heart Defects, Congenital -- surgery -- Periodicals; Cardiac Surgical Procedures -- Periodicals; Child -- Periodicals; Adult -- Periodicals; 618.9212
• DOI: 10.1177/2150135119852037
• Languages: English
• ISSNs: 2150-1351

Abstract

A 38-year-old female with tricuspid atresia and normally related great arteries, initially palliated with Björk modified Fontan, and ultimately converted to extracardiac conduit Fontan, with a history of ventricular tachycardia and hepatitis C virus (HCV) treated with sofosbuvir/ledipasvir, was referred to our center for consideration of combined heart and liver transplantation. The patient's blood group was O with panel reactive antibodies of 52%. She consented to consideration of HCV-positive donors. Fifteen days later, an HCV-positive donor was identified, and she underwent heart transplantation with pulmonary artery reconstruction performed jointly by adult and pediatric transplant surgeons. To our knowledge, this the first time an HCV-positive donor heart has been to transplant an adult with congenital heart disease.