An oxidative cyclization reaction based fluorescent "Turn-On" probe for highly selective and rapid detection of hypochlorous acid. Issue 12 (21st March 2018)

• Record Type: Journal Article
• Authors: Chen, Bo; Fu, Hongyu; Lv, Yaohong; Li, Xin; Han, Yifeng
• Is Part Of: Tetrahedron letters. Volume 59:Issue 12(2018)
• Page Start: 1116
• Page End: 1120
• Publication Date: 2018-03-21
• Subjects: Fluorescent probe -- Hypochlorous acid -- Reaction-based -- Oxidative cyclization -- BODIPY; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.02.018
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: A novel hypochlorous acid-initiated oxidative intramolecular cyclization based fluorescent probe has been developed. The probe features rapid detection kinetics (<15 s). The probe shows high degree of selectivity and sensitivity for HClO. Abstract: A novel fluorescent turn-on probe, PHC1, for the detection of hypochlorous acid has been developed based on hypochlorous acid-initiated oxidative intramolecular cyclization. Endowed by the fast reaction rate, PHC1 features rapid detection kinetics, as well as high degree of selectivity and sensitivity for HClO.