Aerobic oxidative dehydrogenation of N-heterocycles catalyzed by cobalt porphyrin. Issue 10 (7th March 2018)

• Record Type: Journal Article
• Authors: Zhou, Weiyou; Chen, Dongwei; Sun, Fu'an; Qian, Junfeng; He, Mingyang; Chen, Qun
• Is Part Of: Tetrahedron letters. Volume 59:Issue 10(2018)
• Page Start: 949
• Page End: 953
• Publication Date: 2018-03-07
• Subjects: N-Heterocycles -- Cobalt porphyrin -- Oxidative dehydrogenation -- No additive; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.01.094
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: An efficient catalytic procedure was found for the oxidative dehydrogenation of N -heterocycles. Cobalt porphyrin can catalyze the aerobic dehydrogenation without any additives. The catalytic system can tolerate various substrates. Abstract: An efficient catalytic procedure has been developed for the aerobic oxidative dehydrogenation of N -heterocycles by cobalt porphyrin in the absence of any additives. The catalytic system could tolerate various 1, 2, 3, 4-tetrahydroquinoline derivatives and some other N -heterocycles. The corresponding N -heteroaromatics could be obtained in 59–86% yields. The mechanism investigation suggested that the aerobic oxidative dehydrogenation might proceed with imine intermediate through radical paths.