Are There Potential Applications of Fecal Microbiota Transplantation beyond Intestinal Disorders?. (29th July 2019)

• Record Type: Journal Article
• Authors: Zhou, Youlian; Xu, Haoming; Huang, Hongli; Li, Yingfei; Chen, Huiting; He, Jie; Du, Yanlei; Chen, Ye; Zhou, Yongjian; Nie, Yuqiang
• Other Names: Li Wen-Jun Academic Editor.
• Is Part Of: BioMed research international. Volume 2019(2019)
• Publication Date: 2019-07-29
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2019/3469754
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Intestinal microbial dysbiosis is associated with various intestinal and extraintestinal disorders. Fecal microbiota transplantation (FMT), a type of fecal bacteriotherapy, is considered an effective therapeutic option for recurrent Clostridium difficile infection (rCDI) and also has important value in other intestinal diseases including irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). The purpose of this review is to discuss promising therapeutic value in extraintestinal diseases associated with gut microbial dysbiosis, including liver, metabolic, chronic kidney, neuropsychiatric, allergic, autoimmune, and hematological diseases as well as tumors.