Effect of multimodal intervention on postoperative nausea and vomiting in patients undergoing gynecological laparoscopy. Issue 5 (May 2019)

• Record Type: Journal Article
• Authors: Ma, Kai; Wu, Xiuxiu; Chen, Yongquan; Yuan, Hui
• Is Part Of: Journal of international medical research. Volume 47:Issue 5(2019)
• Page Start: 2026
• Page End: 2033
• Publication Date: 2019-05
• Subjects: Postoperative nausea and vomiting -- surgery -- gynecological laparoscopy -- multimodal intervention -- transversus abdominis plane block -- anesthesia; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/0300060519835700
• Languages: English
• ISSNs: 0300-0605

Abstract

Objective: Postoperative nausea and vomiting (PONV) is a common complication in patients undergoing gynecological laparoscopic surgery, and achieving good results is difficult with a single antiemetic method. This study investigated whether multimodal intervention can reduce PONV in patients undergoing gynecological laparoscopic surgery. Methods: A total of 153 patients who underwent gynecological laparoscopic surgery were randomized into the control group and multimodal group. Patients in the multimodal group received dexmedetomidine 1 µg/kg intravenously 15 minutes before induction of anesthesia. A bilateral transversus abdominis plane block was performed with 0.375% ropivacaine 30 mL after induction of anesthesia. Scores of postoperative nausea and vomiting, the visual analog scale, and the Bruggemann comfort scale (BCS) were assessed 24 hours postoperatively. Results: Nausea and vomiting scores were significantly lower at 2, 6, and 24 hours in the multimodal group compared with the control group. BCS scores were significantly higher at 0 to 24 hours in the multimodal group compared with the control group. Conclusions: Multimodal intervention improves PONV and increases patients' comfort. The multimodal approach can also enhance recovery after gynecological laparoscopic surgery.