Treatment Responses to Tooth Whitening in Twins. (16th January 2014)

• Record Type: Journal Article
• Authors: Corby, Patricia M. A.; Biesbrock, Aaron; Gerlach, Robert; Corby, Andrea L.; Moreira, Alexandre; Schork, Nicholas J.; Bretz, Walter A.
• Is Part Of: Twin research and human genetics. Volume 17:Number 1(2014)
• Page Start: 23
• Page End: 26
• Publication Date: 2014-01-16
• Subjects: twins, -- treatment responses, -- tooth whitening, -- heritability; Twins -- Periodicals; Multiple birth -- Periodicals; 618.25
• DOI: 10.1017/thg.2013.87
• Languages: English
• ISSNs: 1832-4274

Abstract

Abstract : The aim of this study was to determine heritability estimates of treatment responses to a 10% hydrogen peroxide strip-based whitening system in twins. Eighty-five twin pairs were randomly assigned to 10% hydrogen peroxide whitening strips or placebo strips without peroxide. Both twins (monozygotic or dizygotic) received the same treatment. Maxillary teeth were treated for 30 minutes twice daily for 7 days. Efficacy was measured objectively as L* (light–dark), a* (red–green), and b* (yellow–blue) color change from digital images at baseline (∆) and day 8. Heritability estimates for tooth whitening treatment responses for changes from day 8 to baseline were obtained using variance-component methodologies. Whitening treatment responses were highly heritable (h 2 = 71.0) for ∆b* and ∆a*( p < .0001), but not for ∆L* (h 2 = 27.0), which was essentially modulated by environmental factors. This study has demonstrated that both genetic and environmental factors significantly contributed to seven-day whitening treatment responses achieved with 10% hydrogen peroxide strips.