Synthetic biology: the many facets of T7 RNA polymerase. Issue 7 (July 2014)

• Record Type: Journal Article
• Authors: Shis, David L; Bennett, Matthew R
• Is Part Of: Molecular systems biology. Volume 10:Issue 7(2014)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2014-07
• Subjects: Molecular biology -- Periodicals; Systems biology -- Periodicals; 572.8
• DOI: 10.15252/msb.20145492
• Languages: English
• ISSNs: 1744-4292

Abstract

Abstract : Split T7 RNA polymerase provides new avenues for creating synthetic gene circuits that are decoupled from host regulatory processes—but how many times can this enzyme be split, yet retain function? New research by Voigt and colleagues (Segall‐Shapiro et al, 2014) indicates that it may be more than you think. Abstract : How many times can T7 RNA polymerase be split, yet retain function? A tripartite T7 RNAP presented by Voigt and colleagues, expands the utility of the enzyme in orthogonal gene circuits that are decoupled from host regulatory processes.