Heart failure with preserved ejection fraction. (June 2014)

• Record Type: Journal Article
• Authors: Alsamara, Mershed; Alharethi, Rami
• Is Part Of: Expert review of cardiovascular therapy. Volume 12:Number 6(2014)
• Page Start: 743
• Page End: 750
• Publication Date: 2014-06
• Subjects: cardiomyopathy -- diastolic dysfunction -- HFpEF -- preserved ejection fraction; Cardiovascular agents -- Research -- Periodicals; 616.12061
• DOI: 10.1586/14779072.2014.911086
• Languages: English
• ISSNs: 1477-9072

Abstract

Abstract : Heart failure with preserved ejection fraction accounts for up to 50% of hospitalized heart failure patients and is associated with significant mortality and morbidity. The pathophysiology is heterogeneous and not very well defined, which explains the lack of disease-specific therapies. The principles of treating heart failure with preserved ejection fraction are controlling volume with diuretics and diet, and controlling the comorbidities, mainly the hypertension. Further research is encouraged to ascertain the key components of the disease that will serve as targets for therapy.