Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy‐related postinflammatory hyperpigmentation. Issue 5 (20th July 2018)

• Record Type: Journal Article
• Authors: Hong, Ji Yeon; Lee, Hae Woong; Park, Kui Young; Kim, Beom Joon; Kim, Myeung Nam
• Is Part Of: Dermatologic therapy. Volume 31:Issue 5(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-07-20
• Subjects: brimonidine -- laser -- postinflammatory hyperpigmentation; Skin -- Diseases -- Periodicals; Dermatology -- Periodicals; 616.5
• DOI: 10.1111/dth.12657
• Languages: English
• ISSNs: 1396-0296

Abstract

Abstract: Brimonidine gel, originally approved for the treatment of facial rosacea, causes direct vasoconstriction and possesses extensive utilization in dermatologic fields. A Q‐switched (QS) neodymium‐doped yttrium aluminum garnet (Nd:YAG) laser is generally used to treat solar lentigo (SL), often leaving unwanted postinflammatory hyperpigmentation (PIH), especially in dark‐skinned individuals. A 58‐year‐old man with Fitzpatrick skin type IV presented to remove solar lentigines from his face. Prior to and after laser treatment, topical brimonidine gel and steroid cream were applied. In this study, we investigated whether topical application of the α‐adrenergic receptor agonist brimonidine could reduce PIH after QS laser treatment of lentigine in a dark‐skinned patient.