A Novel Route to Substituted 2‐(N‐Arylamino)benzothiazoles via Iron‐Promoted C‐S Bond Formation. Issue 1 (3rd January 2019)

• Record Type: Journal Article
• Authors: Pinapati, Srinivasa rao; Mandapati, Usha rani; Tamminana, Ramana; Rudraraju, Ramesh raju
• Is Part Of: ChemistrySelect. Volume 4:Issue 1(2019)
• Page Start: 254
• Page End: 258
• Publication Date: 2019-01-03
• Subjects: 2-Aminobenzothiazoles -- C-S Cross-coupling reactions -- Iron catalyst -- Mild Reaction Conditions -- One pot synthesis; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201803441
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: The synthesis of 2‐aminobenzothiazoles has been demonstrated in the presence of transition metal under mild reaction conditions. In this paper, disubstituted thioureas have also been reported from isothiocyanates at room temperature. Subsequently, C−S cross‐coupling reaction was described for the construction of benzothiazoles using cheap, readily available and air stable Iron catalyst. Moreover, no other byproducts could be observed except target products. Furthermore, control experiments were performed for reveal the mechanism. In addition, a broad range of substrate scope has been explored. Abstract : The synthesis of 2‐aminobenzothiazoles has been demonstrated in the presence of transition metal under mild reaction conditions. In this paper, disubstituted thioureas have also been reported from isothiocyanates at room temperature. Subsequently, C‐S cross‐coupling reaction was described for the construction of benzothiazoles using cheap, readily available and air stable Iron catalyst. Moreover, no other byproducts could be observed except target products. Furthermore, control experiments were performed for reveal the mechanism. In addition, a broad range of substrate scope has been explored.