C(sp3)–H hydroxylation of fluorenes, oxindoles and benzofuranones with a Mg(NO3)2–HP(O)Ph2 oxidation system. Issue 17 (26th July 2019)

• Record Type: Journal Article
• Authors: Hu, Chen; Hong, Gang; Nahide, Pradip D.; He, Yuchen; Zhou, Chen; Kozlowski, Marisa C.; Wang, Limin
• Is Part Of: Organic chemistry frontiers. Volume 6:Issue 17(2019)
• Page Start: 3167
• Page End: 3171
• Publication Date: 2019-07-26
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c9qo00778d
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A novel oxidation system in which magnesium nitrate is used as an oxidant in the presence of diphenylphosphine oxide permits the C(sp 3 )–H hydroxylation of fluorenes, oxindoles, and benzofuranones. Abstract : A novel oxidation system in which magnesium nitrate [Mg(NO3 )2 ] is used as an oxidant in the presence of diphenylphosphine oxide [HP(O)Ph2 ] permits the C(sp 3 )–H hydroxylation of fluorenes, oxindoles, and benzofuranones. This method features high efficiency, good functional group tolerance, and operational simplicity. Its synthetic utility is highlighted by further transformations to valuable organic materials.