High-throughput and ultra-sensitive single-cell profiling of multiple microRNAs and identification of human cancer. Issue 70 (12th August 2019)

• Record Type: Journal Article
• Authors: Li, Lu; Lu, Meng; Fan, Yuanyuan; Shui, Lingling; Xie, Shuting; Sheng, Renjie; Si, Haibin; Li, Qingling; Wang, Yiguo; Tang, Bo
• Is Part Of: Chemical communications. Volume 55:Issue 70(2019)
• Page Start: 10404
• Page End: 10407
• Publication Date: 2019-08-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc05553c
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : We established an efficient method for single-cell multiple miRNA analysis by droplet microfluidics with high sensitivity and high throughput. Abstract : We established an efficient method for single-cell miRNA analysis by droplet microfluidics, which has high sensitivity of single molecule detection and high throughput. Single-cell analysis of multiple miRNAs in various cells shows that miRNA expression is closely related to cancer type. CTC analysis shows that the method is applicable for rare cell analysis.