Coordination-assembled supramolecular nanoplatforms: structural modulation and theranostic applications. (August 2019)

• Record Type: Journal Article
• Authors: Zhang, Han; Kang, Lei; Zou, Qianli; Xin, Xia; Yan, Xuehai
• Is Part Of: Current opinion in biotechnology. Volume 58(2019)
• Page Start: 45
• Page End: 52
• Publication Date: 2019-08
• Subjects: Biotechnology -- Periodicals; 660.6
• DOI: 10.1016/j.copbio.2018.11.007
• Languages: English
• ISSNs: 0958-1669

Abstract

Graphical abstract: Highlights: Coordination-based supramolecular self-assembly is an effective approach for construction of the theranostic nanoplatforms. Coordination-based supramolecular self-assembly is capable of modulating the nanostructures and physicochemical properties. High performance theranostics are highlighted including multiple, responsive and enhanced theranostic applications. Small biomolecules are promising candidates for the development of coordination-based supramolecular nanoplatforms. Abstract : Theranostics possessing great potential in the treatment of various diseases gain attentions in recent years. Coordination-assembled supramolecular nanoplatforms are emerged as promising candidates for theranostic applications. With the facile, robust and versatile fabrication, these systems overcome the drawbacks of many existing theranostic nanoplatforms. Coordination-based supramolecular self-assembly offers the possibility for modulating the physicochemical properties, thus paving the way for theranostic applications. We highlight the most recent advances on the modulation of structures and properties of coordination-assembled supramolecular nanoplatforms and their exploration in theranostic applications. The long-term goal of this field is to achieve high-performance theranostics in clinic.