A Base‐ and Ligand‐Free Copper‐Catalyzed Oxidative Coupling of Terminal Alkyl Alkynes. Issue 1 (7th January 2019)

• Record Type: Journal Article
• Authors: Ying, Wei‐Wei; Bao, Wen‐Hui; Xu, Xu‐Dong; Wang, Yi‐Ning; Song, Si‐Zhe; Liang, Hongze; Dong, Youren; Wei, Wen‐Ting; Liu, Yan‐Yun; Li, Qiang
• Is Part Of: ChemistrySelect. Volume 4:Issue 1(2019)
• Page Start: 298
• Page End: 301
• Publication Date: 2019-01-07
• Subjects: copper-catalyzed -- oxidative coupling -- terminal alkyl alkynes -- 1, 3-diynes; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201803923
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: A practical synthetic route to 1, 3‐diynes from terminal alkyl alkynes through copper‐catalyzed oxidative coupling is developed. The remarkable features of this oxidative coupling including the base‐ and ligand‐free construct of C−C bond, mild reaction conditions, as well as wide substrate scope that is particularly compatible with some terminal alkyl alkynes. Abstract : A practical synthetic route to 1, 3‐diynes from terminal alkyl alkynes through copper‐catalyzed oxidative coupling is developed. The remarkable features of this oxidative coupling including the base‐ and ligand‐free construct of C−C bond, mild reaction conditions, as well as wide substrate scope that is particularly compatible with some terminal alkyl alkynes.