Acyl Radicals from Terminal Alkynes: Photoredox‐Catalyzed Acylation of Heteroarenes. Issue 42 (29th June 2018)

• Record Type: Journal Article
• Authors: Sultan, Shaista; Rizvi, Masood Ahmad; Kumar, Jaswant; Shah, Bhahwal Ali
• Is Part Of: Chemistry. Volume 24:Issue 42(2018)
• Page Start: 10617
• Page End: 10620
• Publication Date: 2018-06-29
• Subjects: acyl radical -- acylation -- heteroarene -- phenylacetylene -- photoredox; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201801628
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: A photoredox‐mediated acylation reaction of electron deficient heteroarenes with terminal alkynes is reported. The method relies on oxidative cleavage of phenylacetylenes for generation of acyl radicals as a key enabling feature. The reaction is regioselective with broad substrate scope. Quantum yield investigations support a radical chain mechanism. Abstract : A photoredox‐mediated acylation reaction of electron‐deficient heteroarenes with terminal alkynes is reported. The method relies on oxidative cleavage of phenylacetylenes for generation of acyl radicals as a key enabling feature. The reaction is regioselective with broad substrate scope.