Prolonged Complete Response in a Pediatric Patient With Primary Peripheral T-Cell Lymphoma of the Central Nervous System. (17th November 2015)

• Record Type: Journal Article
• Authors: Shalabi, Haneen; Angiolillo, Anne; Vezina, Gilbert; Rubenstein, James L.; Pittaluga, Stefania; Raffeld, Mark; Marcus, Leigh
• Is Part Of: Pediatric hematology and oncology. Volume 32:Number 8(2015)
• Page Start: 529
• Page End: 534
• Publication Date: 2015-11-17
• Subjects: CNS tumors -- NHL -- therapy; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Hematologic Diseases -- Child; Hematologic Diseases -- Infant; Neoplasms -- Child; 618.9215
• DOI: 10.3109/08880018.2015.1074325
• Languages: English
• ISSNs: 0888-0018

Abstract

Abstract : We describe a child with a 2-week history of progressive headaches, blurry vision, and intermittent vomiting. Magnetic resonance imaging (MRI) of the brain showed a deep left hemispheric lesion with extension into the corpus callosum. Histology and immunophenotyping of the lesion was consistent with peripheral T-cell lymphoma, not otherwise specified. Chemotherapy was initiated and a complete remission was achieved. This case illustrates that a chemotherapeutic regimen used in adults with central nervous system (CNS) lymphoma can achieve durable remissions in pediatric patients with peripheral T-cell lymphoma, not otherwise specified of the CNS.