Designing for Accelerated Translation (DART) of emerging innovations in health. Issue 2 (June 2019)

• Record Type: Journal Article
• Authors: Ramsey, Alex T.; Proctor, Enola K.; Chambers, David A.; Garbutt, Jane M.; Malone, Sara; Powderly, William G.; Bierut, Laura J.
• Is Part Of: Journal of clinical and translational science. Volume 3:Issue 2/3(2019)
• Page Start: 53
• Page End: 58
• Publication Date: 2019-06
• Subjects: Designing for dissemination and implementation, -- stakeholder partnerships, -- learning health system, -- implementation science, -- precision medicine, -- speed of translation; Clinical medicine -- Research -- Periodicals; Medicine, Experimental -- Periodicals; Human experimentation in medicine -- Periodicals; 616.027
• DOI: 10.1017/cts.2019.386
• Languages: English
• ISSNs: 2059-8661

Abstract

Abstract: Accelerating innovation translation is a priority for improving healthcare and health. Although dissemination and implementation (D&I) research has made significant advances over the past decade, it has attended primarily to the implementation of long-standing, well-established practices and policies. We present a conceptual architecture for speeding translation of promising innovations as candidates for iterative testing in practice. Our framework to D esign forA cceler atedT ranslation (DART) aims to clarify whether, when, and how to act on evolving evidence to improve healthcare. We view translation of evidence to practice as a dynamic process and argue that much evidence can be acted upon even when uncertainty is moderately high, recognizing that this evidence is evolving and subject to frequent reevaluation. The DART framework proposes that additional factors – demand, risk, and cost, in addition to the evolving evidence base – should influence the pace of translation over time. Attention to these underemphasized factors may lead to more dynamic decision-making about whether or not to adopt an emerging innovation or de-implement a suboptimal intervention. Finally, the DART framework outlines key actions that will speed movement from evidence to practice, including forming meaningful stakeholder partnerships, designing innovations for D&I, and engaging in a learning health system.