Half-and-half nails in a pediatric patient after chemotherapy. (2nd October 2015)

• Record Type: Journal Article
• Authors: Afsar, Fatma Sule; Ozek, Gulcihan; Vergin, Canan
• Is Part Of: Cutaneous and ocular toxicology. Volume 34:Number 4(2015:Dec.)
• Page Start: 350
• Page End: 351
• Publication Date: 2015-10-02
• Subjects: Chemotherapy -- half-and-half nail -- nail changes; Dermatotoxicology -- Periodicals; Ocular toxicology -- Periodicals; Ocular pharmacology -- Periodicals; Dermatopharmacology -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.3109/15569527.2014.999861
• Languages: English
• ISSNs: 1556-9527

Abstract

Abstract: Half-and-half nail, characterized by a reddish brown distal band with a sharply demarcated white proximal band, is a specific manifestation of chronic kidney disease, but it is unusual to occur after chemotherapy. We report a seven-year-old girl who developed half-and-half nails in her fingers one month after treatment with modified Berlin-Frankfurt-Munster protocol followed by maintenance therapy with oral methotrexate and 6-mercaptopurine for pre-B acute lymphoblastic leukemia.