Learning From Vitamin B12‐Mediated Reactions: Cobalt(III)–Carbon‐Assisted Catalytic C−H Difluoroacylation of (Hetero)Arenes through Controlled‐Potential Electrolysis. Issue 16 (29th July 2019)

• Record Type: Journal Article
• Authors: Hossain, Md. Jakir; Ono, Toshikazu; Yano, Yoshio; Hisaeda, Yoshio
• Is Part Of: ChemElectroChem. Volume 6:Issue 16(2019)
• Page Start: 4064
• Page End: 4064
• Publication Date: 2019-07-29
• Subjects: Electrochemistry -- Periodicals; 541.37
• DOI: 10.1002/celc.201901155
• Languages: English
• ISSNs: 2196-0216

Abstract

Abstract: Invited for this month's cover picture is the group of Yoshio Hisaeda at Kyushu University (Japan). The cover picture shows the electrochemical activation of a vitamin B12 derivative and the obtained difluoroacylated products. Read the full text of the Article at 10.1002/celc.201900164 . Abstract : "Difluoroacylation of (hetero)arenes catalyzed by a vitamin B12 derivative is reported, driven by a redox change of cobalt ions in organic media. The process consists of three simple steps: 1) the cobalt(I) species of a vitamin B12 derivative, prepared by controlled‐potential electrolysis at −0.8 V vs. Ag/AgCl in DMSO, reacted with BrCF2 CO2 Et to form a cobalt(III)–CF2 CO2 Et complex; 2) the homolysis of this complex released a CF2 CO2 Et radical under visible light irradiation; 3) the generated radical reacted directly with non‐activated (hetero)arenes to form desired fluoroalkylated molecules…" Learn more about the story behind the research featured on the front cover in this issue's Cover Profile. Read the corresponding Article at10.1002/celc.201900164 .