Ranking of Dystonia Severity by Pairwise Video Comparison. Issue 6 (24th March 2016)
- Record Type:
- Journal Article
- Title:
- Ranking of Dystonia Severity by Pairwise Video Comparison. Issue 6 (24th March 2016)
- Main Title:
- Ranking of Dystonia Severity by Pairwise Video Comparison
- Authors:
- Ellermeyer, Tobias
Otte, Karen
Heinrich, Felix
Mansow‐Model, Sebastian
Kayser, Bastian
Lipp, Axel
Seidel, Adrian
Krause, Patricia
Lauritsch, Katharina
Gusho, Elona
Paul, Friedemann
Kühn, Andrea A.
Brandt, Alexander U.
Schmitz‐Hübsch, Tanja - Abstract:
- Abstract: Background: Reviewers of dystonia rating scales agree on the need to assess symptoms more comprehensively. During the development of a quantitative dystonia assessment by video‐perceptive computing, we devised a video‐based severity ranking as a procedure to create a validation standard without the use of clinical scales. Methods: Thirty‐four patients with dystonia (17 with dystonic tremor) and 2 controls were assessed with clinical scales and video‐recordings of 24 short movement tasks. Two to 4 raters compared multiple permutations of videos from 22 subjects, including 2 healthy controls, until a complete rank order was achieved. Inter‐rater agreement was expressed as normalized Kendall tau distance. Spearman correlations of video rank order with clinical scales and self‐rating were repeated for tremor/nontremor subgroups. Results: Normalized Kendall tau distances were <0.3 for 15 items. The video rank order for sitting and head movements correlated with clinical scales for the whole group (rho 0.52–0.87) and in the subgroup without tremor. In the tremor subgroup such correlation was perceived in the 2 items involving sitting. Video rank order correlated with quality of life self‐rating only in 1 item (arms held in front, palm down). Conclusions: The agreement of video rankings between raters is remarkable. The lack of correlation in the tremor subgroup in several items may be interpreted as tremor being considered in video comparisons but not in clinical scales.Abstract: Background: Reviewers of dystonia rating scales agree on the need to assess symptoms more comprehensively. During the development of a quantitative dystonia assessment by video‐perceptive computing, we devised a video‐based severity ranking as a procedure to create a validation standard without the use of clinical scales. Methods: Thirty‐four patients with dystonia (17 with dystonic tremor) and 2 controls were assessed with clinical scales and video‐recordings of 24 short movement tasks. Two to 4 raters compared multiple permutations of videos from 22 subjects, including 2 healthy controls, until a complete rank order was achieved. Inter‐rater agreement was expressed as normalized Kendall tau distance. Spearman correlations of video rank order with clinical scales and self‐rating were repeated for tremor/nontremor subgroups. Results: Normalized Kendall tau distances were <0.3 for 15 items. The video rank order for sitting and head movements correlated with clinical scales for the whole group (rho 0.52–0.87) and in the subgroup without tremor. In the tremor subgroup such correlation was perceived in the 2 items involving sitting. Video rank order correlated with quality of life self‐rating only in 1 item (arms held in front, palm down). Conclusions: The agreement of video rankings between raters is remarkable. The lack of correlation in the tremor subgroup in several items may be interpreted as tremor being considered in video comparisons but not in clinical scales. This supports video‐based ranking as a more comprehensive rating of dystonia and as a possible validation instrument applicable in situations in which no reference standard is available … (more)
- Is Part Of:
- Movement disorders clinical practice. Volume 3:Issue 6(2016)
- Journal:
- Movement disorders clinical practice
- Issue:
- Volume 3:Issue 6(2016)
- Issue Display:
- Volume 3, Issue 6 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 6
- Issue Sort Value:
- 2016-0003-0006-0000
- Page Start:
- 587
- Page End:
- 595
- Publication Date:
- 2016-03-24
- Subjects:
- dystonia -- quantitative assessment -- validation tool
Movement Disorders
Movement disorders -- Periodicals
Movement disorders
Periodicals
Periodicals
616 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%292330-1619 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/mdc3.12340 ↗
- Languages:
- English
- ISSNs:
- 2330-1619
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 5980.317300
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 11390.xml