Topical brimonidine-assisted laser treatment for the prevention of therapy-related erythema and hyperpigmentation. (19th May 2019)

• Record Type: Journal Article
• Authors: Lee, Sang Ju; Ahn, Ga Ram; Seo, Suk Bae; Park, Kui Young; Kim, Beom Joon; Nam Kim, Myeung
• Is Part Of: Journal of cosmetic and laser therapy. Volume 21:Number 4(2019)
• Page Start: 225
• Page End: 227
• Publication Date: 2019-05-19
• Subjects: Brimonidine -- erythema -- laser -- postinflammatory hyperpigmentation; Skin -- Laser surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.477
• DOI: 10.1080/14764172.2018.1516887
• Languages: English
• ISSNs: 1476-4172

Abstract

ABSTRACT: Postinflammatory hyperpigmentation (PIH) and erythema are the most common adverse effects associated with laser treatment, particularly in dark-skinned individuals. Several methods have been used to prevent or minimize these adverse effects; however, to date, no definitive precautions/strategies are known to prevent post-laser PIH and erythema. We investigated whether the topical application of the α-adrenergic receptor agonist brimonidine could reduce laser treatment-related complications such as erythema and PIH.