Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays–Reconnaissance at 5 years after Hebei Spirit oil spill. (February 2018)

• Record Type: Journal Article
• Authors: Liu, Xiaoshan; Jung, Dawoon; Zhou, Kairu; Lee, Sangwoo; Noh, Kiwan; Khim, Jong Seong; Giesy, John P.; Yim, Un Hyuk; Shim, Won Joon; Choi, Kyungho
• Is Part Of: Marine pollution bulletin. Volume 127(2018)
• Page Start: 264
• Page End: 272
• Publication Date: 2018-02
• Subjects: Hebei Spirit oil spill -- H295R -- MVLN -- Endocrine disrupting potential; Marine pollution -- Periodicals; Marine Biology -- Periodicals; Water Pollution -- Periodicals; Mer -- Pollution -- Périodiques; Publications périodiques; Pollution des mers; Lutte antipollution; Electronic journals; 363.7394
• DOI: 10.1016/j.marpolbul.2017.11.055
• Languages: English
• ISSNs: 0025-326X

Abstract

Abstract: Endocrine disrupting potentials were assessed for sediment samples collected near Hebei Spirit oil spill (HSOS) site, between December 2007 and January 2012. For comparison, major crude oil (CO) of HSOS, or its weathered form were assessed. Both raw extracts (REs) and their fractionated samples were tested using H295R and MVLN luc bioassays. In H295R cells, REs of crude and weathered oil (WO), and nine of 14 sediments significantly increased E2 levels, which were correlated with the concentrations of PAHs. Steroidogenic disruption potentials of the sediments generally decreased over time. Among silica fractions of all REs, aromatic hydrocarbons (F2) and polar compounds (F3) caused greater E2 levels. While, in MVLN cell bioassay, only three of 14 sediment REs showed estrogen receptor binding potencies, and no temporal trend was observed. In conclusion, oil spill can cause endocrine disruption in the affected ecosystem through steroidogenic alteration for years, and such potencies attenuate over time. Highlights: Endocrine disrupting potentials persist in the sediments of Taean coastline even at 5 years after Hebei Spirit Oil Spill. However, such potencies of the sediment extracts attenuate over time through weathering. Sediments collected caused endocrine disruption potentials through disruption in sex steroidogenesis. Aromatic hydrocarbons and polar fractions of the oil spill were responsible for the steroidogenic alteration.