Cu-Catalyzed cyanoalkylation of electron-deficient alkenes with unactivated alkyl bromides. Issue 67 (1st August 2019)

• Record Type: Journal Article
• Authors: Wang, Chao; Shang, Qinyu; Qi, Rupeng; Chai, Hongli; Wang, Hongying; Guo, Mengzhun; Xu, Zhaoqing
• Is Part Of: Chemical communications. Volume 55:Issue 67(2019)
• Page Start: 9991
• Page End: 9994
• Publication Date: 2019-08-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc04432a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : We here report the photoinduced Cu-catalyzed cyanoalkylation of electron-deficient alkenes by using alkyl bromides as alkylation reagents. Abstract : We here report the photoinduced Cu-catalyzed cyanoalkylation of electron-deficient alkenes by using alkyl bromides as alkylation reagents. In the reactions, 1°, 2°, and 3° unactivated alkyl bromides with various sensitive functional groups were well tolerated with good yields. Notably, terminal and internal alkenes, as well as alkene-containing peptides, were all tolerated well.