Highly Efficient and Diastereoselective Construction of Tricyclic Pyrrolidine‐Fused Benzo[b]thiophene 1, 1‐dioxide Derivatives via 1, 3‐Dipolar [3 + 2] Cycloaddition. (18th June 2019)
- Record Type:
- Journal Article
- Title:
- Highly Efficient and Diastereoselective Construction of Tricyclic Pyrrolidine‐Fused Benzo[b]thiophene 1, 1‐dioxide Derivatives via 1, 3‐Dipolar [3 + 2] Cycloaddition. (18th June 2019)
- Main Title:
- Highly Efficient and Diastereoselective Construction of Tricyclic Pyrrolidine‐Fused Benzo[b]thiophene 1, 1‐dioxide Derivatives via 1, 3‐Dipolar [3 + 2] Cycloaddition
- Authors:
- Wang, Kai‐Kai
Li, Yan‐Li
Ma, Guo‐Yang
Yi, Meng‐Hao
Zhu, Bao‐Ku - Abstract:
- Abstract : A rapid and highly efficient 1, 3‐dipolar [3 + 2] cycloaddition of nonstabilized azomethine ylides generated in situ with benzo[ b ]thiophene 1, 1‐dioxides as the dipolarophiles has been developed. The efficient method affords tricyclic pyrrolidine‐fused benzo[ b ]thiophene 1, 1‐dioxide derivatives in high to excellent yields (up to 99%) with excellent diastereoselectivities (up to >25:1 dr) under mild reaction conditions. The structure of a typical product was confirmed by X‐ray crystallography. Abstract :
- Is Part Of:
- Journal of heterocyclic chemistry. Volume 56:Number 8(2019)
- Journal:
- Journal of heterocyclic chemistry
- Issue:
- Volume 56:Number 8(2019)
- Issue Display:
- Volume 56, Issue 8 (2019)
- Year:
- 2019
- Volume:
- 56
- Issue:
- 8
- Issue Sort Value:
- 2019-0056-0008-0000
- Page Start:
- 2274
- Page End:
- 2280
- Publication Date:
- 2019-06-18
- Subjects:
- Heterocyclic compounds -- Periodicals
547.59 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/jhet.3591 ↗
- Languages:
- English
- ISSNs:
- 0022-152X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4998.200000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 11379.xml