Morphologic Anomalies of Upper Cervical Vertebrae in Swedish Children Born with Nonsyndromic Cleft Lip and/or Palate Compared to Swedish Children without Cleft. (July 2019)

• Record Type: Journal Article
• Authors: Karsten, Agneta; Sideri, Metaxia; Spyropoulos, Meropi
• Is Part Of: Cleft palate-craniofacial journal. Volume 56:Number 6(2019)
• Page Start: 751
• Page End: 758
• Publication Date: 2019-07
• Subjects: cervical vertebrae -- orofacial clefts -- os odontoideum -- posterior arch deficiency -- vertebral artery canal -- vertebral fusion; Cleft palate -- Periodicals; Skull -- Abnormalities -- Periodicals; Cranial manipulation -- Periodicals; Skull -- Abnormalities -- Surgery -- Periodicals; Face -- Abnormalities -- Surgery -- Periodicals; Fente palatine -- Périodiques; Crâne -- Malformations -- Périodiques; Manipulation crânienne -- Périodiques; Crâne -- Malformations -- Chirurgie -- Périodiques; Face -- Malformations -- Chirurgie -- Périodiques; Cleft palate; Cranial manipulation; Face -- Abnormalities -- Surgery; Skull -- Abnormalities; Skull -- Abnormalities -- Surgery; Cleft Lip; Cleft Palate; Facial Bones -- abnormalities; Skull -- abnormalities; Periodicals; Periodicals; Periodicals; 617.522
• DOI: 10.1177/1055665618808621
• Languages: English
• ISSNs: 1055-6656

Abstract

Objective: To examine and compare the prevalence of morphologic anomalies of the upper cervical vertebrae in Swedish children with nonsyndromic cleft lip and/or palate to Swedish children without cleft. Design: Retrospective study on lateral cephalograms. Setting: Division of Orthodontics, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden. Patients: The cleft group consisted of 325 children (150 girls and 175 boys) born with nonsyndromic cleft lip and/or palate (mean age: 11.1 years). The control group consisted of 325 children without cleft, matched for age and gender. Main Outcome Measures: Lateral cephalograms exposing upper cervical vertebrae (C1-C3) were examined regarding morphologic anomalies such as posterior arch deficiencies, fusion of vertebrae, odontoid anomalies, and deviations of the vertebral artery canal. Results: The prevalence of children with morphologic anomalies of the upper cervical vertebrae was 24.3% (n = 79) in children with cleft and 12.6% (n = 41) in children without cleft. Posterior arch deficiency and vertebral fusion were significantly more frequent in children with cleft ( P < .001). No statistically significant differences were found between the 2 groups regarding odontoid and vertebral artery canal anomalies. Conclusions: Morphologic anomalies of the upper cervical vertebrae in Swedish children with nonsyndromic cleft lip and/or palate were significantly more frequent compared to similar anomalies in Swedish children without cleft.