Electrochemical N-acylation synthesis of amides under aqueous conditions. Issue 16 (26th July 2019)

• Record Type: Journal Article
• Authors: Ke, Fang; Xu, Yiwen; Zhu, Suning; Lin, Xiaoyan; Lin, Chen; Zhou, Sunying; Su, Huimin
• Is Part Of: Green chemistry. Volume 21:Issue 16(2019)
• Page Start: 4329
• Page End: 4333
• Publication Date: 2019-07-26
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c9gc01391a
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : An electrochemical N -acylation of carboxylic acids with amines was reported. Abstract : An electrochemical N -acylation of carboxylic acids with amines was reported. The sustainable TBAB electrocatalysis proceeded with excellent chemoselectivity and positional selectivity, and with ample scope, allowing electrochemical N -acylation under mild reaction conditions at room temperature in water. Moreover, the synthetic utility of the current method is demonstrated by the synthesis of melatonin.