An analytical reconstruction model of the spread-out Bragg peak using laser-accelerated proton beams. (31st May 2017)

• Record Type: Journal Article
• Authors: Tao, Li; Zhu, Kun; Zhu, Jungao; Xu, Xiaohan; Lin, Chen; Ma, Wenjun; Lu, Haiyang; Zhao, Yanying; Lu, Yuanrong; Chen, Jia-er; Yan, Xueqing
• Is Part Of: Physics in medicine & biology. Volume 62:Number 13(2017:Jul.)
• Page Start: 5200
• Page End: 5212
• Publication Date: 2017-05-31
• Subjects: analytical reconstruction model -- spread-out Bragg peak -- laser-accelerated proton beams; Biophysics -- Periodicals; Medical physics -- Periodicals; 610.153
• DOI: 10.1088/1361-6560/aa6fce
• Languages: English
• ISSNs: 0031-9155

Abstract

Abstract: With the development of laser technology, laser-driven proton acceleration provides a new method for proton tumor therapy. However, it has not been applied in practice because of the wide and decreasing energy spectrum of laser-accelerated proton beams. In this paper, we propose an analytical model to reconstruct the spread-out Bragg peak (SOBP) using laser-accelerated proton beams. Firstly, we present a modified weighting formula for protons of different energies. Secondly, a theoretical model for the reconstruction of SOBPs with laser-accelerated proton beams has been built. It can quickly calculate the number of laser shots needed for each energy interval of the laser-accelerated protons. Finally, we show the 2D reconstruction results of SOBPs for laser-accelerated proton beams and the ideal situation. The final results show that our analytical model can give an SOBP reconstruction scheme that can be used for actual tumor therapy.