Trends in documented co-occurring conditions in children with autism spectrum disorder, 2002–2010. (December 2018)

• Record Type: Journal Article
• Authors: Rubenstein, Eric; Schieve, Laura; Wiggins, Lisa; Rice, Catherine; Van Naarden Braun, Kim; Christensen, Deborah; Durkin, Maureen; Daniels, Julie; Lee, Li-Ching
• Is Part Of: Research in developmental disabilities. Volume 83(2018)
• Page Start: 168
• Page End: 178
• Publication Date: 2018-12
• Subjects: Autism spectrum disorder -- Co-occurring conditions -- Trends -- Sex -- Race/ethnicity; Developmental disabilities -- Periodicals; Developmentally disabled -- Research -- United States -- Periodicals; Developmentally disabled children -- Education -- Research -- United States -- Periodicals; Developmental Disabilities -- Periodicals; Disabled -- Periodicals; Mental Retardation -- rehabilitation -- Periodicals; Personnes atteintes de troubles du développement -- Recherche -- États-Unis -- Périodiques; Enfants atteints de troubles du développement -- Éducation -- Recherche -- États-Unis -- Périodiques; Développement, Troubles du -- Recherche -- États-Unis -- Périodiques; 616.858800
• DOI: 10.1016/j.ridd.2018.08.015
• Languages: English
• ISSNs: 0891-4222

Abstract

Highlights: Co-occurring conditions for 8 year-olds with autism increased from 2002 to 2010. Developmental co-occurring conditions had the largest increase over time. Trends in developmental and psychiatric conditions differed in boys and girls. Trends in neurological conditions differed between race/ethnicities. Abstract: Background: Autism spectrumdisorder (ASD) commonly presents with co-occurring medical conditions (CoCs). Little is known about patterns in CoCs in a time of rising ASD prevalence. Aims: To describe trends in number and type of documented CoCs in 8-year-old children with ASD. Methods: We used Autism and Developmental Disabilities Monitoring Network (ADDM) data, a multi-source active surveillance system monitoring ASD prevalence among 8-year-old children across the US. Data from surveillance years 2002, 2006, 2008, and 2010 were used to describe trends in count, categories, and individual CoCs. Results: Mean number of CoCs increased from 0.94 CoCs in 2002 to 1.06 CoCs in 2010 (p < 0.001). The percentage of children with ASD with any CoC increased from 44.5% to 56.4% (p < 0.001). CoCs with the greatest increases were in general developmental disability (10.4% to 14.5%), language disorder (18.9% to 23.6%), and motor developmental disability (10.5% to 15.6%). Sex modified the relationship between developmental (P = 0.02) and psychiatric (P < 0.001) CoCs and surveillance year. Race/ethnicity modified the relationship between neurological conditions (P = 0.04) and surveillance year. Conclusions: The increase in the percentage of children with ASD and CoCs may suggest the ASD phenotype has changed over time or clinicians are more likely to diagnose CoCs.