Eosinophilic enteritis due to cow's milk allergy: Possible cause of anastomosis failure following repair of focal intestinal perforation. Issue 6 (3rd February 2016)

• Record Type: Journal Article
• Authors: Yokoyama, Satoshi; Sekioka, Akinori; Utsunomiya, Hirofumi; Yokoyama, Koji; Ikeda, Yuka; Hara, Shigeto; Yoshida, Akira
• Is Part Of: Pediatrics international. Volume 58:Issue 6(2016)
• Page Start: 493
• Page End: 496
• Publication Date: 2016-02-03
• Subjects: allergen‐specific lymphocyte stimulation test -- anastomosis leakage -- cow's milk allergy -- eosinophilic enteritis; Pediatrics -- Periodicals; 618.92
• DOI: 10.1111/ped.12835
• Languages: English
• ISSNs: 1328-8067

Abstract

Abstract: Reports of cow's milk allergy (CMA) after neonatal gastrointestinal surgery have recently increased. In recent years it has been suggested that the development of CMA after gastrointestinal surgery in newborn infants is due to an immune function. In addition, the development of CMA might be synergistically exacerbated by congenital abnormalities of the intestinal mucosa, general conditional changes and local damage to the intestine by invasive surgery, and poor pre‐ or post‐surgical nutrition. CMA manifests as a variety of symptoms, such as mild vomiting and bloody stool, decreased activity, poor oral intake, and ileus. CMA may also rarely cause gastrointestinal perforation. Here, we report the case of a newborn infant who developed CMA following repair of focal small intestinal perforation, in which eosinophilic enteritis was suspected to be a possible cause of anastomosis leakage.