Effects of biodegradable hydrogel spacer injection on contralateral submandibular gland sparing in radiotherapy for head and neck cancers. Issue 1 (January 2018)

• Record Type: Journal Article
• Authors: Rao, Avani D.; Coquia, Stephanie; De Jong, Robert; Gourin, Christine; Page, Brandi; Latronico, Diane; Dah, Samson; Su, Lin; Clarke, Stephen; Schultz, Jeffrey; Rosati, Lauren M.; Fakhry, Carole; Wong, John; DeWeese, Theodore L.; Quon, Harry; Ding, Kai; Kiess, Ana
• Is Part Of: Radiotherapy and oncology. Volume 126:Issue 1(2018)
• Page Start: 96
• Page End: 99
• Publication Date: 2018-01
• Subjects: Submandibular gland -- Xerostomia -- Radiation therapy; Oncology -- Periodicals; Radiotherapy -- Periodicals; Tumors -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiothérapie -- Périodiques; Cancérologie -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9940642
• DOI: 10.1016/j.radonc.2017.09.017
• Languages: English
• ISSNs: 0167-8140

Abstract

Abstract: Xerostomia is the most common late toxicity after head and neck radiation. We demonstrate injection of a hydrogel spacer anteriorly displacing the submandibular gland. This procedure enables reduced dose to the displaced submandibular gland in cadaveric models of oropharynx cancer treated with IMRT, with potential implications in reducing xerostomia risk.