The interaction of 4-hydroxymethyl isoindolines with dehydrobenzene. Synthesis of 3-phenylaminomethyldihydrobenzo[c]furanes. Issue 8 (25th February 2015)

• Record Type: Journal Article
• Authors: Varlamov, Alexey V.; Guranova, Natalia I.; Borisova, Tatiana N.; Toze, Flavien A.A.; Ovcharov, Maxim V.; Kristancho, Sindi; Voskressensky, Leonid G.
• Is Part Of: Tetrahedron. Volume 71:Issue 8(2015)
• Page Start: 1175
• Page End: 1181
• Publication Date: 2015-02-25
• Subjects: Phthalans -- Isobenzofurans -- Dehydrobenzene -- Isoindolines -- Recyclization -- Diarylamines; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2015.01.022
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: 2-Alkyl or 2-aryl-substituted 4-hydroxymethylisoindolines smoothly undergo intramolecular recyclization through reaction with arynes to give isobenzofurans with good yields. Graphical abstract: