Second-trimester Ultrasound and Neuropathologic Findings in Congenital Zika Virus Infection. Issue 12 (December 2018)

• Record Type: Journal Article
• Authors: Ho, Cheng-Ying; Castillo, Nicolas; Encinales, Liliana; Porras, Alexandra; Mendoza, Alejandro Rico; Lynch, Rebecca; Nemirovsky, Amy; Mantus, Grace; DeBiasi, Roberta L.; Bethony, Jeffrey M.; Simon, Gary L.; Chang, Aileen Y.
• Is Part Of: Pediatric infectious disease journal. Volume 37:Issue 12(2018)
• Publication Date: 2018-12
• Subjects: Zika -- microcephaly -- fetal brain anomalies -- congenital infection -- neuronal apoptosis; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000002080
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : Zika virus is a mosquito-borne virus that causes congenital Zika syndrome, characterized by microcephaly and other fetal brain anomalies. This case report presents a case of Zika virus–related fetal brain anomalies including pathologic evidence of cerebral neuronal apoptosis and macrophage infiltrates and intracerebral calcification, ventriculomegaly and corpus callosum dysgenesis detected by ultrasound at 18 weeks of pregnancy.