Uptake and Tracer Kinetic of O-(2-(18)F-fluoroethyl)-L-Tyrosine in Meningioma. (January 2019)

• Record Type: Journal Article
• Authors: Basse, Victor; Dissaux, Gurvan; Seizeur, Romuald; Bourhis, David; Querellou, Solène
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 1(2019)
• Publication Date: 2019-01
• Subjects: FET PET -- meningioma -- glioma -- TBR -- grading; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002350
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: 18 F-fluoroethyltyrosine (FET) is a well-established PET tracer for the imaging of cerebral gliomas. Recent studies reported interest in meningiomas. A study published by Cornelius et al concludes that FET PET may provide additional information for noninvasive grading of meningiomas. Indeed, the combination of tumor background ratio with a cutoff value of 2.3 associated with time activity curve pattern slightly improved the differentiation of high-grade from low-grade meningiomas (accuracy, 92%; P = 0.001). We present the case of a 75-year-old man that underlined the need to confirm the performance of these tools (curve pattern, tumor background ratios) to characterize meningiomas.