Juvenile Nasal Angiofibroma on 68Ga-PSMA PET/CT: Opening New Frontiers. (February 2019)

• Record Type: Journal Article
• Authors: Sakthivel, Pirabu; Prashanth, Arun; Thakar, Alok; Kumar, Rajeev; Kumar, Rakesh
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 2(2019)
• Publication Date: 2019-02
• Subjects: angiofibroma -- PSMA PET/CT -- juvenile nasopharyngeal angiofibroma; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002387
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: The prostate-specific membrane antigen (PSMA) is highly expressed in prostatic cancer. However, PSMA expression is also noted in various benign and malignant nonprostatic neoplasms in the endothelial cells of tumor-associated neovasculature. We performed 68 Ga-PSMA PET/CT in a 14-year-old boy with juvenile nasal angiofibroma (JNA) to explore its theranostic potential. The scan revealed high uptake in the lesion. Performance of PSMA PET/CT in JNA opens up new frontiers with respect to radiological staging, early recurrence identification, and perhaps even radioligand therapy of residual/recurrent JNAs in the future.