Rib Fractures Mimicking Bone Metastases in 18F-PSMA-1007 PET/CT for Prostate Cancer. (January 2019)

• Record Type: Journal Article
• Authors: Panagiotidis, Emmanouil; Paschali, Anna; Giannoula, Evanthia; Chatzipavlidou, Vasiliki
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 1(2019)
• Publication Date: 2019-01
• Subjects: 18F-PSMA-1007 PET/CT -- prostate cancer -- bone metastases -- rib fracture; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002354
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Prostate-specific membrane antigen (PSMA) is a membrane glycoprotein that is overexpressed in prostate cancer cells. It is also expressed in other normal tissues and several other malignant and benign diseases. We present a case of a 69-year-old man with history of prostate adenocarcinoma who underwent 18 F-PSMA-1007 PET/CT due to suspected biochemical recurrence. PET/CT showed 18 F-PSMA-1007 uptake in healing rib fractures with no other pathologic findings. Clinicians reporting 18 F-PSMA-1007 PET/CT should be aware of this potential pitfall, especially in nontypical trauma pattern (eg, solitary osseous lesion) mimicking bone metastases.