A unique combination of KI/ZnFe2O4 as a catalyst for oxidative Strecker reaction. (13th November 2018)

• Record Type: Journal Article
• Authors: Ghandi, Leila; Kazemi Miraki, Maryam; Karimi, Meghdad; Radfar, Iman; Heydari, Akbar
• Is Part Of: Applied organometallic chemistry. Volume 33:Number 1(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-11-13
• Subjects: methylarenes -- nanocrystalline spinel ferrites -- oxidative Strecker reaction -- α‐aminonitriles; Organometallic chemistry -- Periodicals; Organometallic compounds -- Periodicals; 547.05
• DOI: 10.1002/aoc.4616
• Languages: English
• ISSNs: 0268-2605

Abstract

Abstract : α‐Aminonitriles as key intermediates for the preparation of α‐amino acid derivatives, amides, diamines, peptides, proteins and heterocycles were synthesized through methylarene oxidation in the Strecker reaction using a unique combination of KI/ZnFe2 O4 as the best catalyst and aqueous tert ‐butyl hydroperoxide as oxidant. A wide range of amines and methylarenes were converted to the corresponding products. Operational simplicity, short reaction time and recyclability of the catalyst are advantages of this protocol. Abstract : α‐Amino nitriles were synthesized through the methylarenes oxidation in Strecker reaction by a unique combination of KI/ZnFe2 O4 as the best catalyst and aqueous ter‐butyl hydroperoxide as an oxidant in good to high yields.