Clostridium Perfringens Bacteremia with Acute Hemolytic Anemia in the Setting of Endometrial Malignancy. Issue 1 (March 2019)

• Record Type: Journal Article
• Authors: Cypher, Luke R.; Sullivan, Christopher; Jones, Ryan; Phillips, Angelina
• Is Part Of: Academic forensic pathology. Volume 9:Issue 1/2(2019)
• Page Start: 127
• Page End: 133
• Publication Date: 2019-03
• Subjects: Forensic pathology -- Clostridium perfringens -- Bacteremia -- Acute hemolytic anemia -- Endometrial malignancy; Forensic pathology -- Periodicals; Forensic pathology; Electronic journals; Periodicals; 614.1
• DOI: 10.1177/1925362119851240
• Languages: English
• ISSNs: 1925-3621

Abstract

Acute intravascular hemolysis is a rare and often lethal complication of Clostridium perfringens septicemia.Clostridium perfringens is an anaerobic, gram-positive spore-forming rod which is commonly implicated in cases of food poisoning, gas gangrene, and severe hemolytic anemia in humans via the alpha-toxin (phospholipase C). We report an interesting and rare case of a 72-year-old woman who developed massive intravascular hemolysis secondary to C perfringens bacteremia in the setting of poorly differentiated high-grade endometrial malignancy.