Nanobiointerfaces: Human Platelet Membrane Functionalized Microchips with Plasmonic Codes for Cancer Detection (Adv. Funct. Mater. 30/2019). (23rd July 2019)

• Record Type: Journal Article
• Authors: Kumar, Sumit; Han, Jae‐A; Michael, Issac J.; Ki, Dongyeob; Sunkara, Vijaya; Park, Juhee; Gautam, Shreedhar; Ha, Hong Koo; Zhang, Liangfang; Cho, Yoon‐Kyoung
• Is Part Of: Advanced functional materials. Volume 29:Number 30(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-07-23
• Subjects: cancer -- extracellular vesicles -- plasmonic coupling -- platelets; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201970205
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number1902669, Yoon‐Kyoung Cho and co‐workers describe a microfluidic chip equipped with a platelet membrane‐cloaked surface, the "PLT‐Chip, " which takes advantage of the strong and specific interaction between platelets and cancer‐derived extracellular vesicles. The PLT‐Chip accurately detects cancer using ultra‐small volumes (1 µL) of patient's plasma samples, with high sensitivity.