Cover Feature: Fluorescence Properties of Flavin Semiquinone Radicals in Nitronate Monooxygenase (ChemBioChem 13/2019). (24th June 2019)

• Record Type: Journal Article
• Authors: Su, Dan; Kabir, Mohammad Pabel; Orozco‐Gonzalez, Yoelvis; Gozem, Samer; Gadda, Giovanni
• Is Part Of: Chembiochem. Volume 20:Number 13(2019)
• Page Start: 1614
• Page End: 1614
• Publication Date: 2019-06-24
• Subjects: dark states -- density functional calculations -- flavin semiquinones -- fluorescence -- radicals; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.201900373
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : The neutral flavin semiquinone radical stabilized in the active site of nitronate monooxygenase shows novel fluorescence behavior. It displays a broad UV–visible absorption spectrum in the near‐UV and visible light range and emits red fluorescence when excited with yellow and red light. Such fluorescence is not observed when using excitation light of a shorter wavelength. How the excitation‐wavelength‐dependent fluorescence behavior violates the Kasha–Vavilov rule is discussed in depth in the communication by G. Gadda et al. onpage 1646 in Issue 13, 2019 (DOI:10.1002/cbic.201900016 ).