Front Cover: Multifunctional Clickable Reagents for Rapid Bioorthogonal Astatination and Radio‐Crosslinking (ChemPlusChem 7/2019). Issue 7 (30th April 2019)

• Record Type: Journal Article
• Authors: Denk, Christoph; Wilkovitsch, Martin; Aneheim, Emma; Herth, Matthias M.; Jensen, Holger; Lindegren, Sture; Mikula, Hannes
• Is Part Of: ChemPlusChem. Volume 84:Issue 7(2019)
• Page Start: 772
• Page End: 772
• Publication Date: 2019-04-30
• Subjects: bioorthogonal chemistry -- click chemistry -- multicomponent reactions -- radiochemistry -- radiolabeling; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cplu.201900238
• Languages: English
• ISSNs: 2192-6506

Abstract

Abstract : The front cover shows immobilized astatine‐labeled reagents that have been sterically shielded with polyethylene chains by rapid bioorthogonal ligation leading to increased stability of the radiolabel in biological media. These multifunctional and bioorthogonal 211 At reagents can efficiently be prepared by rapid click assembly and simultaneous astatination. More details can be found in the Communication by Hannes Mikula and co‐workers onpage 775 in Issue 7, 2019 (DOI:10.1002/cplu.201900114 ).