Inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients. Issue 8 (3rd July 2019)

• Record Type: Journal Article
• Authors: Dagnelie, Marie‐Ange; Montassier, Emmanuel; Khammari, Amir; Mounier, Carine; Corvec, Stéphane; Dréno, Brigitte
• Is Part Of: Experimental dermatology. Volume 28:Issue 8(2019)
• Page Start: 961
• Page End: 967
• Publication Date: 2019-07-03
• Subjects: acne -- inflammatory skin diseases -- innate immunity -- microbiology -- microbiome; Dermatology -- Periodicals; 616.5
• DOI: 10.1111/exd.13988
• Languages: English
• ISSNs: 0906-6705

Abstract

Abstract: Acne is the most common inflammatory skin disease, affecting up to 85% of the 11‐30 years old world population. Skin microbiota appears as a key player involved in several skin dermatoses physiopathology. Here, we show that inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients but also on the face of patients where acne was scored as mild to moderate, comparing with healthy controls. Changes were observed particularly on skin commensals Propionibacteriaceae, Staphylococcaceae and Enterococcaceae families, suggesting the importance of the balance between skin commensals to maintain skin homeostasis and control skin inflammatory process.