Bone Regeneration: A Magnesium‐Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration (Adv. Sci. 12/2019). Issue 12 (19th June 2019)

• Record Type: Journal Article
• Authors: Lin, Sihan; Yang, Guangzheng; Jiang, Fei; Zhou, Mingliang; Yin, Shi; Tang, Yanmei; Tang, Tingting; Zhang, Zhiyuan; Zhang, Wenjie; Jiang, Xinquan
• Is Part Of: Advanced science. Volume 6:Issue 12(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-06-19
• Subjects: 3D culture systems -- biomaterials -- developmental microenvironment -- magnesium -- vascularized bone regeneration; Science -- Periodicals; 505
• DOI: 10.1002/advs.201970069
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : Inspired by the correlation between MagT1 and embryonic bone development, a magnesium‐enriched 3D culture system is fabricated to provide embryonic‐like microenvironment for stem cells in article number1900209 by Wenjie Zhang, Xinquan Jiang, and co‐workers. Mg 2+ via MagT1 stimulates both osteogenic differentiation and neovascularization. An obvious vascularized bone regeneration is achieved in vivo using such magnesium‐enriched cell vehicles.