Four new C19-diterpenoid alkaloids from Aconitum hemsleyanum var. circinatum. Issue 9 (2nd September 2019)

• Record Type: Journal Article
• Authors: He, Dan; Liu, Wang-Yan; Xiong, Jiao; Xu, Jun-Ju; Shen, Yong
• Is Part Of: Journal of Asian natural products research. Volume 21:Issue 9(2019)
• Page Start: 833
• Page End: 841
• Publication Date: 2019-09-02
• Subjects: C19-diterpenoid alkaloids -- Aconitum hemsleyanumvar. circinatum -- spectroscopy; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2018.1500555
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Four new C19-diterpenoid alkaloids, hemaconitines A–D (1 –4 ), were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated as 19R-hydroxyl-secoyunnaconitine (1 ), (3R)-hydroxyl-liwaconitine (2 ), 14-anisoyl-leucanthumsine E (3 ), and 19R -acetonyl-8-O-methyltalatisamine (4 ) by extensive spectroscopic analysis (IR, UV, HR-ESI-MS, 1D, and 2D NMR). Graphical Abstract: