A beverage containing orange pomace improves laxation and modulates the microbiome in healthy adults: A randomised, blinded, controlled trial. (September 2019)

• Record Type: Journal Article
• Authors: Dennis-Wall, Jennifer C.; Burns, Alyssa M.; Solch, Rebecca J.; Ukhanova, Maria; Dahl, Wendy J.; Christman, Mary C.; Boileau, Thomas; Brauchla, Mary; Shin, Jin-E; Nieves, Carmelo; Mai, Volker; Langkamp-Henken, Bobbi
• Is Part Of: Journal of functional foods. Volume 60(2019)
• Publication Date: 2019-09
• Subjects: Dietary fibre -- Pomace -- Pectin -- Intestinal microbiota -- Bifidobacteria -- Healthy adults; ASA24 Automated Self-Administered 24-h (dietary recall) -- BSFS Bristol stool form scale -- FW flavoured water control group -- FDA Food and Drug Administration -- GSRS Gastrointestinal Symptom Rating Scale -- ITT intent-to-treat -- LAB lactic acid bacteria -- OJ orange juice -- OJ90 orange juice with 90 g pomace -- OJ180 orange juice with 180 g pomace -- OTU operational taxonomic unit -- PP per-protocol; Functional foods -- Analysis -- Periodicals; Food -- Biotechnology -- Periodicals; Nutrition -- Periodicals; 613.2
• DOI: 10.1016/j.jff.2019.103438
• Languages: English
• ISSNs: 1756-4646

Abstract

Graphical abstract: Highlights: Healthy adults increased daily fibre intake by drinking orange juice with pomace. Stool frequency increased and stools were softer with pomace. When consumed daily, pomace provided physiological benefit. Bifidobacteria do not appear to mediate this benefit. Abstract: The aim was to assess whether citrus pomace increases stool frequency in healthy adults. In this randomised, blinded, controlled trial, healthy adults (62% females) received a beverage containing pomace (473 mL/day, providing 10 g fibre/day, n = 111) or control ( n = 110) for 3 weeks. Stool frequency, Bristol Stool Form Scale (BSFS), and Gastrointestinal Symptom Rating Scale (GSRS) scores were self-assessed. 24-h diet recalls were completed once/week. Stool microbiota were analysed by 16S rRNA sequencing and qPCR. Mean total daily fibre intake was higher with pomace vs. control ( P < 0.0001). Mean weekly stool frequency was higher, indicating improved laxation, with pomace vs. control ( P = 0.0281) and increased from baseline with pomace ( P = 0.0003) but was unchanged with control. Mean BSFS scores were higher with pomace vs. control ( P = 0.04). GSRS indigestion syndrome scores, specifically symptoms of gas and bloating, were higher with pomace, suggesting fermentation. Pomace intake increased faecal OTUs corresponding to Lachnospiraceae and Ruminococcaceae . Clinicaltrials.gov #NCT02979496 .