Biosynthesis and cytotoxic activity of lead oxide nanoparticles. Issue 4 (2nd October 2018)

• Record Type: Journal Article
• Authors: Miri, Abdolhossien; Sarani, Mina; Hashemzadeh, Alireza; Mardani, Zahra; Darroudi, Majid
• Is Part Of: Green chemistry letters and reviews. Volume 11:Issue 4(2018)
• Page Start: 567
• Page End: 572
• Publication Date: 2018-10-02
• Subjects: α-PbO-NPs -- β-PbO-NPs -- biosynthesis -- cytotoxicity; Green chemistry -- Periodicals; 540
• DOI: 10.1080/17518253.2018.1547926
• Languages: English
• ISSNs: 1751-8253

Abstract

ABSTRACT: Lead oxide (PbO) is known as an important industrial material. It is a semiconductor that has two crystalline forms, litharge (tetragonal crystalline structure) and massicot (orthorhombic crystalline structure). In this research, lead oxide nanoparticles (PbO-NPs) have been synthesized through the utilization of gelatin as a stabilizer, while its cytotoxic effects were investigated on Neueo2A cancer cell line. The generation of PbO-NPs was confirmed by the UV-Vis spectroscopy, PXRD, TG-DTA, EDX, and FESEM. The results of diffraction patterns of synthesized nanoparticles show the formation of both form α-PbO-NPs (tetragonal) and β-PbO-NPs (orthorhombic). The particles size of synthesized PbO-NPs was calculated to be around 10–20 nm. The cytotoxic activity of the synthesized PbO-NPs indicated that concentrations under 30 μg/mL have insignificant toxicity. GRAPHICAL ABSTRACT: