[3+2] Cyclization of Azidotrimethylsilane with Quinoxalin‐2(1H)‐Ones to Synthesize Tetrazolo[1, 5‐a]quinoxalin‐4(5H)‐Ones. Issue 23 (30th October 2018)

• Record Type: Journal Article
• Authors: Yang, Qiming; Zhang, Yuecheng; Sun, Qian; Shang, Kun; Zhang, Hong‐Yu; Zhao, Jiquan
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 23(2018)
• Page Start: 4509
• Page End: 4514
• Publication Date: 2018-10-30
• Subjects: Cyclization -- Copper-catalyzed -- Azidotrimethylsilane -- Quinoxalin-2(1H)-one -- Tetrazole; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201801076
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A convenient and efficient protocol for the synthesis of thetetrazolo[1, 5‐ a ]quinoxalin‐4(5 H )‐ones via copper‐catalyzed [3+2] cyclization of azidotrimethylsilane with quinoxalin‐2(1 H )‐ones under mild conditions has been disclosed. This practical protocol is compatible with a variety of functional groups and provides an access to functionalized tetrazolo[1, 5‐ a ]quinoxalin‐4(5 H )‐ones from readily available and safe starting materials. Abstract :