Modeling-based determination of physiological parameters of systemic VOCs by breath gas analysis: a pilot study. (6th May 2015)

• Record Type: Journal Article
• Authors: Unterkofler, Karl; King, Julian; Mochalski, Pawel; Jandacka, Martin; Koc, Helin; Teschl, Susanne; Amann, Anton; Teschl, Gerald
• Is Part Of: Journal of breath research. Volume 9:Number 3(2015:Sep.)
• Publication Date: 2015-05-06
• Subjects: breath gas analysis -- volatile organic compounds -- modeling -- metabolic rates -- production rates -- isoprene -- Farhi equation; Volatile organic compounds -- Analysis -- Periodicals; Clinical chemistry -- Periodicals; Bad breath -- Periodicals; Bad breath -- Treatment -- Periodicals; Bad breath -- Diagnosis -- Periodicals; 616.0756
• DOI: 10.1088/1752-7155/9/3/036002
• Languages: English
• ISSNs: 1752-7155

Abstract

Abstract: In this paper we develop a simple two compartment model which extends the Farhi equation to the case when the inhaled concentration of a volatile organic compound (VOC) is not zero. The model connects the exhaled breath concentration of systemic VOCs with physiological parameters such as endogenous production rates and metabolic rates. Its validity is tested with data obtained for isoprene and inhaled deuterated isoprene-D5.