Comparison of Laparoscopic and Open Surgery for Patients With Borderline Ovarian Tumors. Issue 9 (November 2018)

• Record Type: Journal Article
• Authors: Jung, Hee-Jung; Park, Jeong-Yeol; Kim, Dae-Yeon; Suh, Dae-Shik; Kim, Jong-Hyeok; Kim, Yong-Man; Kim, Young-Tak; Nam, Joo-Hyun
• Is Part Of: International journal of gynecological cancer. Volume 28:Issue 9(2018)
• Publication Date: 2018-11
• Subjects: Borderline ovarian tumor -- Minimally invasive surgery -- Laparoscopic surgery -- Surgical outcomes -- Oncologic outcomes; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1097/IGC.0000000000001358
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Objectives: The aim of this study was to compare surgical and oncologic outcomes of open and laparoscopic surgery in patients with borderline ovarian tumors (BOTs). Materials and Methods: This study included patients with BOTs who underwent open (n = 433) or laparoscopic (n = 210) surgery between 1990 and 2015. Surgical outcomes, perioperative morbidity, and disease-free survival and overall survival were compared. Results: There was no significant difference in age, histologic type of tumor, and laterality of tumor. However, body mass index was slightly higher for the open surgery group ( P = 0.046). The open surgery group had a higher serum cancer antigen 125 level ( P < 0.001), larger tumor size ( P < 0.001), more frequent radical surgery ( P = 0.001), higher stage ( P = 0.034), and higher incidence of invasive implants ( P = 0.035). The operative time ( P < 0.001), time interval to return of bowel movement ( P < 0.001), and length of postoperative hospital stay ( P < 0.001) were significantly shorter and estimated blood loss was significantly less ( P < 0.001) in the laparoscopic group. Perioperative complications were documented in 5 (2.4%) patients in the laparoscopic surgery group and 17 (3.9%) in the open surgery group ( P = 0.064). Twenty-three (5.3%) patients in the open surgery group and 9 (4.3%) in the laparoscopic surgery group had recurrence ( P = 0.902) at a median follow-up of 57 months. The 10-year disease-free survival was 96% and 97% for the open and laparoscopic groups, respectively ( P = 0.851), with no significant difference between the groups after adjusting for independent factors (odds ratio, 1.0; 95% confidence interval, 0.4–2.4; P = 0.999). The 10-year overall survival was 99% for both groups, respectively ( P = 0.441). Conclusions: Laparoscopic surgery and open surgery showed similar survival outcomes in BOTs. The surgical outcomes of laparoscopic surgery were more favorable.